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Botox, Botox Cosmetic, Latisse, Fillers, Peels and other Facial Rejuvenation issues

Botox ®, Botox Cosmetic ®, Restylane ®, Juvederm ™, Latisse ™, Chemical Peels and related Facial Rejuvenation topics will be discussed in this blog.
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Sunday, April 6, 2008

New Botox Study and the Media Hype

Researches of the Italian National Research Council's Institute of Neuroscience recently observed that botulinum toxin injected into rats whisker muscles moved away from the site of the injection and could be detected just days later in brain stem cells. While this has started a feeding frenzy for media headlines, the findings of the study need to be placed into perspective:

  • A laboratory preparation of botulinum toxin was used in the study, not the popular anti-wrinkle drug Botox Cosmetics sold by Allergan. Data suggests that different preparations react differently in laboratories and clinical practice.

  • The anatomy of rats is very different from the anatomy of humans and the findings can not be directly translated.

  • Millions of Botox treatments have been administered since 1987 without any known long term side effects.

  • The study is not conclusive and contradicts previous findings, but as a medical doctor I always support additional research to get conclusive research data.


Botox at the DermaSmooth Clinic

The DermaSmooth Clinic is following a very strict patient safety policy. Our number one priority is the safety and well being of our patients. We only use drugs and products that have proven safe and affective through extensive research and years of clinical administration. In addition, our clients are only treated by highly trained and experienced medical doctors.


Other voices to the study:

"There is no chance that this could happen to a human. Botox is a poison and a single unit of botulism is a 50 per cent lethal dose for a white mouse, but it is very different for human beings. The doses [used for cosmetic application] are relatively much smaller and it has much more local effects.
If used appropriately, Botox is a wonderful drug, and you are much more likely to encounter problems from injecting it into the wrong area than from it migrating anywhere."

Dr Douglas McGeorge
President of the British Association of Aesthetic Plastic Surgeons
(source: independent.co.uk)

"The idea that there could be some transmission of this to the central nervous system needs to be followed up. But this treatment has been used on millions of people for years."
Mathew Avram
Director of Massachusetts General Hospital's Dermatology, Laser and Cosmetic Center, in Boston
(source: my13la.com)

"The new findings should not deter any physicians, nor should patients be discouraged. Botox is important for treating many diseases. From a basic science point of view, this has more relevance for studying the transport of proteins."
J. Oliver Dolly,
Director of the International Centre for Neurotherapeutics at Dublin City University in Ireland,
(source: sciencenews.org)

"Botox has been used for more than 25 years with very few complications, unless you overdose. ... I don't think fear is warranted." He adds that the toxin's ability to spread might have an upside, allowing doctors to treat brain-based disorders such as epilepsy."
Christopher von Bartheld, Neuroscientist
University of Nevada School of Medicine in Reno.
(source: sciencemag.com)

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This blog if hosted on a Californian website and Dr. Davoodifar, Susan Davoodifar MD, Inc. and the DermaSmooth Clinic provide California-based services. All information in this blog is presented in summary form, is general in nature and is intended for educational and informational purposes only. It is not intended as or as a substitution of a medical consultation. Always consult your doctor.

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